for a quick and conservative adoption of scons, GenerateConfigH provides excellent example.

in fact, that example could be even simplified a little bit more.

it should be noted that it's still easy to provide the user the usual interface to a source package:

$ ./configure
$ make
$ make install

just dump the m4 and autotools, in favour of python and scons. (i think it should be perfectly ok if one has nothing against make, especially when one's project is small.)